Publication

Determination toxic effects of Hystrix Brachyura Bezoar extracts using cancer cell lines and embryo zebrafish (Danio rerio) models and identification of active principles through GC-MS analysis

HASNIZA BINTI AMNO

Published : 07 September 2020

Authors :Al’aina Yuhainis Firus Khan, Qamar Uddin Ahmed, Tanzina Sharmin Nippun, Ayah Hilles, Tara K. Jalal, Teh Lay Kek, Mohd Zaki Salleh, Suzita Mohd Noor, Azman Seeni, Alfi Khatib, Ridhwan Abdul Wahab

Titles of Publication :Determination toxic effects of Hystrix Brachyura Bezoar extracts using cancer cell lines and embryo zebrafish (Danio rerio) models and identification of active principles through GC-MS analysis

Journal Name :Journal of Ethnopharmacology

Quartile :3.690

Impact Factor :Q1

Link :https://doi.org/10.1016/j.jep.2020.113138

Description :The findings revealed that all three PBs aqueous extracts possessed anticancer activity and exhibited significant toxicological effects on zebrafish embryos with high teratogenicity index. Hence, its use as an anticancer agent requires further investigation and medical attentions to determine its safe dose

Determination toxic effects of Hystrix Brachyura Bezoar extracts using cancer cell lines and embryo zebrafish (Danio rerio) models and identification of active principles through GC-MS analysis

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