Authors :Manogaran, M., Vuanghao, L., & Mohamed, R.
Titles of Publication :Gynura procumbens ethanol extract and its fractions inhibit macrophage derived foam cell formation
Journal Name :Journal of Ethnopharmacology
Quartile :Q1
Impact Factor :3.690
Description :In conclusion, G. procumbens ethanol extract and its fractions inhibit the formation of macrophage derived foam cell by reducing TNF-? and IL-1? expression, which usually highly expressed in atherosclerotic plaques, suppressing scavenger receptor LOX-1 gene that binds oxLDL but induced ABCA-1 gene that mediate lipid efflux from macrophages