Publication

Potential of Lyophilized Platelet Concentrates for Craniofacial Tissue Regenerative Therapies

Published : 10 March 2021

ASSOCIATE PROFESSOR DR SITI NOOR FAZLIAH MOHD NOOR
Authors :Ngah, NA (Ngah, Nurul Aida); Ratnayake, J (Ratnayake, Jithendra); Cooper, PR (Cooper, Paul R.); Dias, GJ (Dias, George J.); Tong, DC (Tong, Darryl C.); Noor, SNFM (Mohd Noor, Siti Noor Fazliah); Hussaini, HM (Hussaini, Haizal Mohd)
Titles of Publication :Potential of Lyophilized Platelet Concentrates for Craniofacial Tissue Regenerative Therapies
Journal Name :Molecules
Quartile :Q2
Impact Factor :3.267 
Description :The use of platelet concentrates (PCs) in oral and maxillofacial surgery, periodontology, and craniofacial surgery has been reported. While PCs provide a rich reservoir of autologous bioactive growth factors for tissue regeneration, their drawbacks include lack of utility for long-term application, low elastic modulus and strength, and limited storage capability. These issues restrict their broader application. This review focuses on the lyophilization of PCs (LPCs) and how this processing approach affects their biological and mechanical properties for application as a bioactive scaffold for craniofacial tissue regeneration.
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